WHAT DOES THR777 MEAN?

What Does thr777 Mean?

What Does thr777 Mean?

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The submitting Business for this submitted (SCV) report. This column also incorporates the SCV accession and Edition amount, the date this SCV to start with appeared in ClinVar, as well as date that this SCV was very last up to date in ClinVar.

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The amount of variants in ClinVar for this gene, together with smaller sized variants in the gene and bigger CNVs that overlap or totally incorporate the gene.

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This sequence alter impacts codon 777 with the GAA mRNA. It's really a 'silent' improve, this means that it doesn't alter the encoded amino acid sequence on the GAA protein. This variant also falls at the last nucleotide of exon 16, which is A part of the consensus splice site for this exon. This variant is existing in populace databases (rs375311693, gnomAD 0.03%). This variant has not been reported during the literature in people today influenced with GAA-connected circumstances.

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